Class will be held in 1060 Bainer, Mondays and Wednesdays 4:10pm–6:00pm
The lecture slides will be posted
Office Hours will be in person or by Zoom by request
Introductory Statistics with R (Textbook: ISwR)
https://cran.r-project.org/bin/windows/base/
https://www.rstudio.com/products/rstudio/
https://rstudio-education.github.io/hopr/starting.html
Statistics for Experimenters, Second Edition.
Box, GEP, Hunter, JS, and Hunter, WG, Wiley, 2005.
January 5. 2026
Reading: BHH Chapter 1
Presentation: Lecture 1: Introduction to Experimental Design
Install R and (optionally) R Studio (links above)
Practice using ISwR or the R Studio Education link
January 7, 2026
Reading: BHH Chapter 1
Presentation: Lecture 2: Introduction to Experimental Design (part 2)
Homework: See end of slides for Lecture 2—submit code and results. Due 1/16/26.
January 12, 14 2026
Reading: BHH Chapter 2
Presentation: Lecture 3: R Basics
Homework: See end of slides—(Does not have to be handed in.)
January 19, 2026
Martin Luther King Day
No Class
January 14, 21, 2026
Reading: BHH Chapter 2
Presentation: Lecture 4: Regression and Calibration
Homework:
January 21, 2026
Reading:
Presentation: Lecture 5: Introduction to Assays
January 26, 2026
Reading:
Presentation: Lecture 6: Measurement and Analytical Error
Homework: Homework 2: see slides 24 and 25—Due 2/4/26
Currie et al. (1995)
Rocke and Lorenzato (1995)
Wilson, Rocke, Durbin, and Kahn (2004)
zinc data
January 28, February 2, 2026
Reading: BHH, Chapters 3 and 4.
Presentation: Lecture 7: Fully Randomized and Randomized Block Designs
Presentation: Homework Advice
Homework: HW 3, due 2/13/26
BHH2 R Package Reference Manual
BHH2 R Package Vignette
BsMD R Package Reference Manual
BHH Data Sets (zip file)
February 4, 2026
Reading:
Presentation: Lecture 8: PCR, Immunoassays, RNA-Seq, Mass Spectrometry
February 11, 2026
Midterm Exam
February 9, 18, 2026
Reading: BHH, Chapter 5.
Presentation: Lecture 9: Factorial Designs at Two Levels
Homework: HW 4, due 2/27/26
February 16, 2026
President's Day
No Class
February 23, 25, 2026
Reading: BHH, Chapter 6.
Presentation: Lecture 10: Fractional Factorial Designs
Hellstrand (1989)
Quinlan (1985)
March 2, 2026
Reading: BHH, Chapter 8.
Presentation: Lecture 11: Transformation and Variance
Take Home Final Exam: due 3/13/2026
March 4, 2026
Reading:
Presentation: Lecture 12: Multiple Comparisons
Homework:
March 9, 2026
Reading:
Presentation: Lecture S1: Introduction to Survival Analysis
Homework:
March 11, 2026
Reading:
Presentation: Lecture S2: Survival Data and Methods
Homework: