BIM 283: Advanced Design of Experiments for Biomedical Engineers
Winter 2025

Course Syllabus

Instructor: David M. Rocke (dmrocke at ucdavis.edu)

Announcements

Class will be held in 1060 Bainer, Tuesdays and Thursdays, 10:00–11:50
The lecture slides will be posted

Class January 7 and 9 will be by Zoom
Office Hours week of Jan 6 will be by Zoom by request

R Resources

Introductory Statistics with R (Textbook: ISwR)

https://cran.r-project.org/bin/windows/base/

https://www.bigbookofr.com

https://www.rstudio.com/products/rstudio/

https://rstudio-education.github.io/hopr/starting.html

Textbook:

Statistics for Experimenters, Second Edition.
Box, GEP, Hunter, JS, and Hunter, WG, Wiley, 2005.

Class Notes:

January 7. 2025 (Zoom)
Reading:
BHH Chapter 1
Presentation: Lecture 1: Introduction to Experimental Design
Note: Class this week will be by Zoom. Link to follow.

Install R and (optionally) R Studio (links above)
Practice using ISwR or the R Studio Education link

January 9, 2025 (Zoom)
Reading:
BHH Chapter 1
Presentation: Lecture 2: Introduction to Experimental Design (part 2)
Homework: See end of slides for Lecture 2—submit code and results. Due 1/16/25.
Note: Class this week will be by Zoom. Link to follow.

January 14, 2025
Reading:
BHH Chapter 2
Presentation: Lecture 3: R Basics
Homework: See end of slides—Due 1/23/25 (Does not have to be handed in.)

January 16, 2025
Reading:
BHH Chapter 2
Presentation: Lecture 4: Regression and Calibration
Homework:

January 21, 2025
Reading:

Presentation: Lecture 5: Introduction to Assays

January 23, 2025
Reading:

Presentation: Lecture 6: Measurement and Analytical Error
Homework: See slides 24 and 25—Due 1/30/25

Currie et al. (1995)
Rocke and Lorenzato (1995)
Wilson, Rocke, Durbin, and Kahn (2004)
zinc data